As the year progresses, several high-profile celebrities have been open about facing serious health challenges. Whether through diagnoses that have dramatically affected their lives or ongoing health struggles, these public figures continue to inspire their fans by showing resilience and strength. Here’s a look at the celebrities who are dealing with serious illnesses in 2025.
1. Eric Dane – Battling ALS (Amyotrophic Lateral Sclerosis)
Actor Eric Dane, best known for his roles in Grey’s Anatomy and Euphoria, has publicly shared his battle with amyotrophic lateral sclerosis (ALS), a devastating neurological disease that affects motor neurons in the brain and spinal cord. ALS leads to progressive muscle weakness and loss of motor function, making everyday tasks increasingly difficult.
Dane’s diagnosis, which he revealed in 2025, has brought awareness to ALS and its effects. The actor has spoken about his physical and emotional struggles, while also advocating for research and support for those battling the disease. While the diagnosis has been a tough reality for Dane, he has shown immense bravery in sharing his journey with the public.
2. Elton John – Struggling with Significant Vision Loss
Music legend Elton John has been battling significant vision loss in 2025. The 77-year-old icon has struggled with eye problems for several years, and his condition has worsened. While exact details about his diagnosis have not been fully disclosed, the singer has spoken openly about the challenges he faces due to his deteriorating sight. Despite this setback, John has continued to perform, using technology and assistance to help him manage his performances and daily life.
John’s openness about his condition has helped bring attention to the importance of vision care, particularly for those with conditions that can lead to significant impairments later in life. His ongoing work as a performer and philanthropist serves as an inspiration to many.
3. Justin Timberlake – Fighting Lyme Disease and Its Symptoms
Pop superstar Justin Timberlake has been battling Lyme disease, a tick-borne illness that affects multiple systems in the body. Timberlake’s struggles with Lyme disease have been marked by various symptoms, including fatigue, joint pain, and neurological issues, which have made it difficult for him to maintain his usual pace in the entertainment industry.
While Lyme disease can be effectively treated with antibiotics in its early stages, chronic Lyme can lead to long-lasting effects. Timberlake has openly discussed his health challenges, raising awareness about the importance of early diagnosis and treatment for Lyme disease. His public journey with the illness has helped reduce stigma around the condition and encouraged fans to take proactive steps in managing their own health.
4. Teddi Mellencamp – Battling Cancer Spread to Brain and Lungs
Teddi Mellencamp, best known for her role on The Real Housewives of Beverly Hills, has faced a tragic and difficult health battle. In 2025, Mellencamp revealed that her cancer had spread to her brain and lungs, adding a layer of complexity to her fight against the disease. She has been open with her followers on social media about the ups and downs of her diagnosis, showing great strength and determination.
Her willingness to share her journey with cancer has given her fans a deeper connection with her. It has also raised awareness for the importance of early cancer screenings, while highlighting the power of community support during difficult times. Teddi’s resilience is an inspiration to others going through similar battles.
5. Billy Joel – Living with Normal Pressure Hydrocephalus (Brain Disorder)
Music legend Billy Joel has been diagnosed with normal pressure hydrocephalus (NPH), a neurological condition that causes fluid to build up in the brain. NPH can lead to symptoms such as difficulty walking, memory problems, and urinary incontinence. While the condition is treatable, it requires careful management.
Joel has spoken about how the disease has affected his daily life, but he has also remained active, continuing to perform for his fans. His openness about NPH has shed light on a less commonly known condition, helping to encourage people to seek medical advice if they experience similar symptoms.
6. Michael Bolton – Fighting Glioblastoma (Brain Cancer)
Singer and songwriter Michael Bolton has been diagnosed with glioblastoma, an aggressive form of brain cancer that often presents significant challenges for treatment. Glioblastoma is known for its rapid progression and poor prognosis, but Bolton has continued to undergo treatment in hopes of slowing the disease’s progression. Despite his diagnosis, Bolton has maintained a positive attitude and continues to perform and create music.
Bolton’s battle with glioblastoma has brought attention to the importance of brain cancer research and the need for better treatment options. His story serves as a reminder of the strength needed to face one of the most difficult health challenges.
7. Lupita Nyong’o – Struggling with Uterine Fibroids
Oscar-winning actress Lupita Nyong’o has revealed that she is living with uterine fibroids, which are non-cancerous growths in the uterus. While fibroids are common, they can cause symptoms such as severe pain, heavy bleeding, and complications during pregnancy. Nyong’o has spoken candidly about how the condition has affected her life, sharing both the physical and emotional toll it has taken.
By discussing her experience with fibroids, Nyong’o has raised awareness about a condition that affects millions of women but is often not talked about in the public sphere. Her openness is helping to reduce the stigma surrounding reproductive health issues and is encouraging other women to seek treatment and support.
8. Billy Porter – Battling Sepsis-Immune Dysfunction
Actor and performer Billy Porter has been diagnosed with sepsis-immune dysfunction, a condition where the body’s immune system responds to infection with excessive inflammation. This disorder can lead to widespread organ damage if not treated promptly. Porter’s illness has significantly impacted his ability to perform and travel, but he has remained vocal about his health journey.
Porter’s bravery in sharing his health struggle has helped raise awareness for both sepsis and immune disorders. He has encouraged people to seek medical help at the first sign of infection and has been an advocate for better understanding and care of sepsis, which can sometimes be life-threatening.
